tear film

Human Meibum and Tear Film Derived (O-Acyl)-Omega-Hydroxy Fatty Acids as Biomarkers of Tear Film Dynamics in Meibomian Gland Dysfunction and Dry Eye Disease

We investigated OAHFAs derived from human meibum and tear film in meibomian gland dysfunction and dry eye disease

Human meibum and tear film derived (O-acyl)-omega-hydroxy fatty acids in meibomian gland dysfunction

This study evaluates tear film and meibum-derived OAHFAs in meibomian gland dysfunction

Human Meibum and Tear Film Derived (O-acyl)-Omega-Hydroxy Fatty Acids as Biomarkers of Tear Film Dynamics

Meibomian gland dysfunction (MGD) produces alterations in the tear film (TF) lipid layer that causes excessive evaporation of tears from the ocular surface and subsequent increased osmolarity leading to dry eye disease. However, the molecular …

Inflammatory proteins associated with contact lens-related dry eye

This study evaluates the levels and regulation of tear film inflammatory proteins in contact lens-related dry eye (CLDE).

Human precorneal tear film and lipid layer dynamics in meibomian gland dysfunction

This study evaluates the precorneal tear film (PCTF) and lipid layer (TFLL) thicknesses and thinning rates in meibomian gland dysfunction (MGD) using a combined ultra-high-resolution optical coherence tomography (OCT) and thickness dependent fringe (TDF) interferometry system.

The role of (O-acyl)-Omega-Hydroxy Fatty Acids in Human Lipid Layer Structure and Function in Health and Meibomian Gland Dysfunction (PI, Jason Nichols)

This project aims to investigate the role of (O-acyl)-Omega-Hydroxy Fatty Acids in alterations of human tear film lipid layer as a basis for formulating novel therapeutics for meibomian gland dysfunction.